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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN1
All Species:
19.7
Human Site:
S380
Identified Species:
33.33
UniProt:
Q16512
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16512
NP_002732.3
942
103932
S380
G
S
L
S
G
R
S
S
L
K
A
E
A
E
N
Chimpanzee
Pan troglodytes
XP_512443
1169
127241
S607
G
S
L
S
G
R
S
S
L
K
A
E
A
E
N
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
K448
S
E
V
L
A
V
L
K
V
D
N
R
V
V
G
Dog
Lupus familis
XP_542019
1076
118222
S513
G
S
L
S
G
R
S
S
L
K
V
E
A
E
N
Cat
Felis silvestris
Mouse
Mus musculus
P70268
946
104392
S383
G
S
L
S
G
R
S
S
L
R
G
E
A
E
N
Rat
Rattus norvegicus
Q63433
946
104449
S383
G
S
L
S
G
R
S
S
L
K
G
E
A
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
K435
N
E
V
L
A
V
L
K
V
D
N
R
V
V
G
Chicken
Gallus gallus
XP_422357
1013
114806
N408
A
K
A
G
I
S
K
N
L
L
K
T
D
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689331
948
107057
T393
S
G
S
V
S
G
K
T
P
L
K
T
D
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
K155
R
F
V
V
H
S
Y
K
R
F
T
F
C
D
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
V228
P
G
N
K
A
D
A
V
E
E
L
G
K
E
I
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
G287
F
L
D
N
Q
R
H
G
M
C
L
N
L
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
T346
S
N
S
A
I
Q
S
T
S
A
K
N
V
Q
G
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Q434
F
I
K
G
A
R
P
Q
G
M
D
R
L
G
R
Conservation
Percent
Protein Identity:
100
79.3
38.7
83
N.A.
91.6
91.9
N.A.
42.2
57.6
N.A.
66.7
N.A.
29
N.A.
27.8
48.5
Protein Similarity:
100
79.9
52.6
84.3
N.A.
94.7
94.6
N.A.
56.1
72.1
N.A.
79.5
N.A.
42.8
N.A.
43.4
61.7
P-Site Identity:
100
100
0
93.3
N.A.
86.6
93.3
N.A.
0
6.6
N.A.
6.6
N.A.
0
N.A.
6.6
13.3
P-Site Similarity:
100
100
13.3
93.3
N.A.
93.3
93.3
N.A.
13.3
20
N.A.
13.3
N.A.
20
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
28.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.4
45.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
29
0
8
0
0
8
15
0
36
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
15
8
0
15
15
0
% D
% Glu:
0
15
0
0
0
0
0
0
8
8
0
36
0
58
0
% E
% Phe:
15
8
0
0
0
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
36
15
0
15
36
8
0
8
8
0
15
8
0
8
22
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
15
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
8
8
8
0
0
15
22
0
29
22
0
8
0
0
% K
% Leu:
0
8
36
15
0
0
15
0
43
15
15
0
15
0
15
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
8
8
8
8
0
0
0
8
0
0
15
15
0
0
36
% N
% Pro:
8
0
0
0
0
0
8
0
8
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
8
8
0
8
0
0
0
0
0
8
0
% Q
% Arg:
8
0
0
0
0
50
0
0
8
8
0
22
0
0
8
% R
% Ser:
22
36
15
36
8
15
43
36
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
15
0
0
8
15
0
0
0
% T
% Val:
0
0
22
15
0
15
0
8
15
0
8
0
22
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _